Artículos científicos sobre la COVID-19


Scientific Advisory Group for Emergencies (SAGE): Coronavirus (COVID-19) response.(Reino Unido)

– Informe del Imperial College – 16 de marzo de 2020:

Informe técnico. Enfermedad por coronavirus, COVID-19. Centro de Coordinación de Alertas y Emergencias Sanitarias.

– Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome. 23 de enero de 2020 [citado 7 de febrero de 2020]; Disponible en:

– Novel Coronavirus (2019-nCoV) situation reports [Internet].[citado 23 de enero de 2020]. Disponible en:

– Paules CI, Marston HD, Fauci AS. Coronavirus Infections—More Than Just the Common Cold. JAMA [Internet]. 23 de enero de 2020[citado 6 de febrero de 2020]; Disponible en:

– World health Organization. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) [Internet]. 2020. Disponible en:

– Cyranoski D. Mystery deepens over animal source of coronavirus. Nature. marzo de 2020;579(7797):18-9.

– Cui J, Li F, Shi Z-L. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol. 2019;17(3):181-92.

– Saif LJ. Animal coronavirus: lessons for SARS [Internet]. National Academies Press (US); 2004 [citado 6 de febrero de 2020]. Disponible en:

– Hung LS. The SARS epidemic in Hong Kong: what lessons have we learned? J R Soc Med [Internet]. agosto de 2003 [citado 6 de febrero de 2020];96(8):374-8. Disponible en:

– To KK-W, Tsang OT-Y, Chik-Yan Yip C, Chan K-H, Wu T-C, Chan JMC, etal. Consistent detection of 2019 novel coronavirus in saliva. Clin Infect Dis Off Publ Infect Dis Soc Am. 12 de febrero de 2020;

– Doremalen N van, Bushmaker T, Morris D, Holbrook M, Gamble A, Williamson B, etal. Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1. medRxiv [Internet]. 13 de marzo de 2020 [citado 16 de marzo de 2020];2020.03.09.20033217. Disponible en:

– Kampf G,Todt D, Pfaender S, Steinmann E. Persistence of coronaviruses on inanimate surfaces and its inactivation with biocidal agents. J Hosp Infect. 6 de febrero de 2020;

– World health Organization. Water, sanitation, hygiene and waste management for COVID-19 [Internet]. 2020. Disponible en:

– European Centre for Disease Prevention and Control. Infection prevention and control for the care of patients with 2019-nCoV in healthcare settings [Internet]. 2020 feb. Disponible en: Infection prevention and control for the care of patients with 2019-nCoV in healthcare settings

– Booth TF, Kournikakis B, Bastien N, Ho J, Kobasa D, Stadnyk L, etal. Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units. J Infect Dis. 1 de mayo de 2005;191(9):1472-7.

– Yeo C, Kaushal S, Yeo D. Enteric involvement of coronaviruses: is faecal-oral transmission of SARS-CoV-2 possible? Lancet Gastroenterol Hepatol. 19 de febrero de 2020;

– Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, etal. First Case of 2019 Novel Coronavirus in the United States. N Engl J Med [Internet]. 31 de enero de 2020 [citado 6 de febrero de 2020];0(0):null. Disponible en:

– Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, etal. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronaviruspneumonia in Wuhan, China: a descriptive study. Lancet Lond Engl. 30 de enero de 2020;

– Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, etal. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet [Internet]. 12 de febrero de 2020 [citado 13 de febrero de 2020];0(0). Disponible en:

– Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, etal. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med [Internet]. 28 de febrero de 2020 [citado 6 de marzo de 2020]; Disponible en:

– Li Q, Guan X, Wu P,Wang X, Zhou L, Tong Y, etal. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia. N Engl J Med [Internet]. 29 de enero de 2020 [citado 6 de febrero de 2020]; Disponible en:

– Wu JT, Leung K, Leung GM. Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study. The Lancet [Internet]. 31 de enero de 2020 [citado 6 de febrero de 2020];0(0). Disponible en:

– Riou J, Althaus CL. Pattern of early human-to-human transmission of Wuhan 2019 novel coronavirus (2019-nCoV), December 2019 to January 2020. Eurosurveillance [Internet]. 30 de enero de 2020 [citado 6 de febrero de 2020];25(4):2000058. Disponible en:

– Huang LL, Shen SP, Yu P, Wei YY. [Dynamic basic reproduction number based evaluation for current prevention and control of COVID-19 outbreak in China]. Zhonghua Liu Xing Bing Xue Za Zhi Zhonghua Liuxingbingxue Zazhi. 1 de marzo de 2020;41(4):466-9.

– Zhang S, Diao M, Yu W, Pei L, Lin Z, Chen D. Estimation of the reproductive number of Novel Coronavirus (COVID-19) and the probable outbreak size on the Diamond Princess cruise ship: A data-driven analysis. Int J Infect Dis IJID Off Publ Int Soc Infect Dis. 22 de febrero de 2020;

– Burke RM. Active Monitoring of Persons Exposed toPatients with Confirmed COVID-19 —United States, January–February 2020. MMWR Morb Mortal Wkly Rep [Internet]. 2020 [citado 4 de marzo de 2020];69. Disponible en:

– Liu Y, Eggo RM, Kucharski AJ. Secondary attack rate and superspreading events for SARS-CoV-2. Lancet Lond Engl. 27 de febrero de 2020;

– Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, etal. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumoniain Wuhan, China. JAMA. 7 de febrero de 2020;

– Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C, etal. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany. N Engl J Med [Internet]. 30 de enero de 2020 [citado 4 de febrero de 2020];0(0):null. Disponible en:

– Kai Kupferschmidt. Study claiming new coronavirus can be transmitted by people without symptoms was flawed. Science [Internet]. 3 de febrero de 2020; Disponible en:

– Chan JF-W, Yuan S, Kok K-H, To KK-W, Chu H, Yang J, etal. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet Lond Engl. 24 de enero de 2020;

– Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z, etal. SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients. N Engl J Med. 19 de febrero de 2020;

– Huang R, Xia J, Chen Y, Shan C, Wu C. A family cluster of SARS-CoV-2 infection involving 11 patients in Nanjing, China. Lancet Infect Dis. 28 de febrero de 2020;

– Bai Y, Yao L, Wei T, Tian F, Jin D-Y, Chen L, etal. Presumed Asymptomatic Carrier Transmission of COVID-19. JAMA [Internet]. 21 de febrero de 2020 [citado 6 de marzo de 2020]; Disponible en:

– Tong Z-D, Tang A, Li K-F, Li P, Wang H-L, Yi J-P, etal. Potential Presymptomatic Transmission of SARS-CoV-2, Zhejiang Province, China. Emerg Infect Dis [Internet]. 2020 [citado 17 de marzo de 2020];26. Disponible en:

– Anderson RM, Heesterbeek H, Klinkenberg D, Hollingsworth TD. How will country-based mitigation measures influence the course of the COVID-19 epidemic? The Lancet [Internet]. 9 de marzo de 2020 [citado 17 de marzo de 2020];0(0). Disponible en:

– Hellewell J, Abbott S, Gimma A, Bosse NI, Jarvis CI, Russell TW, etal. Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts. Lancet Glob Health. 28 de febrero de 2020;

– Ganyani T, Kremer C, Chen D, Torneri A, Faes C, Wallinga J, etal. Estimating the generation interval for COVID-19 based on symptom onset data. medRxiv [Internet]. 8 de marzo de 2020 [citado 17 de marzo de 2020];2020.03.05.20031815. Disponible en:

– Pan Y, Zhang D, Yang P, Poon LLM, Wang Q. Viral load of SARS-CoV-2 in clinical samples. Lancet Infect Dis. 24 de febrero de 2020;

– Informe sobre la situación de COVID-19 en España. CNE. SiVies. CNM (ISCIII); 2020 mar.

– Clinical characteristics of 2019 novel coronavirus infection in China [Internet]. [citado 11 de febrero de 2020]. Disponible en:

– Battegay M, Kuehl R, Tschudin-Sutter S, Hirsch HH, Widmer AF, Neher RA. 2019-novel Coronavirus (2019-nCoV): estimating the case fatality rate -a word of caution. Swiss Med Wkly. 27 de enero de 2020;150:w20203.

– Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, etal. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet Lond Engl. 24 de enero de 2020;

– Wu P, Hao X, Lau EHY, Wong JY, Leung KSM, Wu JT, etal. Real-time tentative assessment of the epidemiological characteristics of novel coronavirus infections in Wuhan, China, as at 22 January 2020. Euro Surveill Bull Eur Sur Mal Transm Eur Commun Dis Bull. enero de 2020;25(3).

– Paules CI, Marston HD, Fauci AS. Coronavirus Infections-More Than Just the Common Cold. JAMA. 23 de enero de 2020;

– Galanti M, Birger R,Ud-Dean M, Filip I, Morita H, Comito D, etal. Longitudinal active sampling for respiratory viral infections across age groups. Influenza Other Respir Viruses. 2019;13(3):226-32.

-Killerby ME, Biggs HM, Haynes A, Dahl RM, Mustaquim D, Gerber SI, etal. Human coronavirus circulation in the United States 2014-2017. J Clin Virol Off Publ Pan Am Soc Clin Virol. 2018;101:52-6.

-Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, etal. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet Lond Engl. 30 de enero de 2020;

– Wu C, Liu Y, Yang Y, Zhang P, Zhong W, Wang Y, etal. Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods. Acta Pharm Sin B [Internet]. 27 de febrero de 2020 [citado 5 de marzo de 2020]; Disponible en:

– Paraskevis D, Kostaki EG, Magiorkinis G, Panayiotakopoulos G, Sourvinos G, Tsiodras S. Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event. Infect Genet Evol [Internet]. 1 de abril de 2020 [citado 7 de febrero de 2020];79:104212. Disponible en:

– Munster VJ, Koopmans M, van Doremalen N, van Riel D, de Wit E. A Novel Coronavirus Emerging in China -Key Questions for Impact Assessment. N Engl J Med. 24 de enero de 2020;

– Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, etal. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 3 de febrero de 2020;

-Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2. Science [Internet]. 4 de marzo de 2020 [citado 5 de marzo de 2020]; Disponible en:

– Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh C-L, Abiona O, etal. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science [Internet]. 19 de febrero de 2020 [citado 5 de marzo de 2020]; Disponible en:

– Tikellis C,Thomas MC. Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease. Int J Pept. 2012;2012:256294.

-Garabelli PJ, Modrall JG, Penninger JM, Ferrario CM, Chappell MC. Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart. Exp Physiol. mayo de 2008;93(5):613-21.

– Stewart JA, Lazartigues E, Lucchesi PA. The angiotensin converting enzyme 2/Ang-(1-7) axis in the heart: a role for MAS communication? Circ Res. 21 de noviembre de 2008;103(11):1197-9.

– Kassiri Z, Zhong J, Guo D, Basu R, Wang X, Liu PP, etal. Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction. Circ Heart Fail. septiembre de 2009;2(5):446-55.

– Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, etal. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature. 7 de julio de 2005;436(7047):112-6.

– Liu Y, Yang Y, Zhang C, Huang F, Wang F, Yuan J, etal. Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Sci China Life Sci. marzo de 2020;63(3):364-74.

– Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA, etal. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 27 de noviembre de 2003;426(6965):450-4.

– Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, etal. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med. agosto de 2005;11(8):875-9.

– The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. Vital Surveillances: The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19). China CDC Wkly [Internet]. febrero de 2020; Disponible en:

– Pan X, Chen D, Xia Y, Wu X, Li T, Ou X, etal. Asymptomatic cases in a family cluster with SARS-CoV-2 infection. Lancet Infect Dis. 19 de febrero de 2020;

– Field Briefing: Diamond Princess COVID-19 Cases, 20 Feb Update [Internet]. [citado 4 de marzo de 2020]. Disponible en:

– Mizumoto K, Kagaya K, Zarebski A, Chowell G. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Eurosurveillance [Internet]. 12 de marzo de 2020 [citado 16 de marzo de 2020];25(10):2000180. Disponible en:

– Hu Z, Song C, Xu C, Jin G, Chen Y, Xu X, etal. Clinical Characteristics of 24 Asymptomatic Infections with COVID-19 Screened among Close Contacts in Nanjing, China. medRxiv [Internet]. 25 de febrero de 2020 [citado 6 de marzo de 2020];2020.02.20.20025619. Disponible en:

– Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, etal. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med [Internet]. 24 de febrero de 2020 [citado 6 de marzo de 2020];0(0). Disponible en:

-Bi Q, Wu Y, Mei S, Ye C, Zou X, Zhang Z, etal. Epidemiology and Transmission of COVID-19 in Shenzhen China: Analysis of 391 cases and 1,286 of their close contacts. medRxiv [Internet]. 4 de marzo de 2020 [citado 17 de marzo de 2020];2020.03.03.20028423. Disponible en:

– Cai JH, Wang XS, Ge YL, Xia AM, Chang HL, Tian H, etal. [First case of 2019 novel coronavirus infection in children in Shanghai]. Zhonghua Er Ke Za Zhi Chin J Pediatr. 4 de febrero de 2020;58(0):E002.

– Kam K-Q, Yung CF, Cui L, Lin Tzer Pin R, Mak TM, Maiwald M, etal. A Well Infant with Coronavirus Disease 2019 (COVID-19) with High Viral Load. Clin Infect Dis Off Publ Infect Dis Soc Am. 28 de febrero de 2020;

– Ferrario Carlos M., Jessup Jewell, Chappell Mark C., Averill David B., Brosnihan K. Bridget, Tallant E. Ann, etal. Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2. Circulation [Internet]. 24 de mayo de 2005 [citado 17 de marzo de 2020];111(20):2605-10. Disponible en:

– Moskowitz DW, Johnson FE. The central role of angiotensin I-converting enzyme in vertebrate pathophysiology. [Internet]. undefined. 2004 [citado 16 de marzo de 2020]. Disponible en: /paper/The-central-role-of-angiotensin-I-converting-enzyme-Moskowitz-Johnson/11ad6b23adfb8f141983dccc9883ff6de060b2cd

– WONG CK, LAM CWK, WU AKL, IP WK, LEE NLS, CHAN IHS, etal. Plasma inflammatory cytokines and chemokines in severe acute respiratorysyndrome. Clin Exp Immunol [Internet]. abril de 2004;136(1):95-103. Disponible en:

– Zheng Y-Y, Ma Y-T, Zhang J-Y, Xie X. COVID-19 and the cardiovascular system. Nat Rev Cardiol [Internet]. 5 de marzo de 2020 [citado 16 de marzo de 2020];1-2. Disponible en:

– Wu Q, Zhou L, Sun X, Yan Z, Hu C, Wu J, etal. Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection. Sci Rep [Internet]. 22 de agosto de 2017 [citado 16 de marzo de 2020];7(1):1-12. Disponible en:

– Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia -Zhu -Translational Pediatrics [Internet]. [citado 6 de marzo de 2020]. Disponible en:

– Honda-Okubo Y, Barnard D, Ong CH, Peng B-H, Tseng C-TK, Petrovsky N. Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology. J Virol. marzo de 2015;89(6):2995-3007.

– Deng Y, Lan J, Bao L, Huang B, Ye F, Chen Y, etal. Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus. Emerg Microbes Infect. 4 de abril de 2018;7(1):60.

– Modjarrad K, Roberts CC, Mills KT, Castellano AR, Paolino K, Muthumani K, etal. Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial. Lancet Infect Dis. septiembre de 2019;19(9):1013-22.

– Lin J-T, Zhang J-S, Su N, Xu J-G, Wang N, Chen J-T, etal. Safety and immunogenicity from a phase I trial of inactivated severe acute respiratory syndrome coronavirus vaccine. Antivir Ther. 2007;12(7):1107-13.

Martin JE, Louder MK, Holman LA, Gordon IJ, Enama ME, Larkin BD, etal. A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial. Vaccine. 25 de noviembre de 2008;26(50):6338-43.

Matz KM, Marzi A, Feldmann H. Ebola vaccine trials: progress in vaccine safety and immunogenicity. ExpertRev Vaccines. diciembre de 2019;18(12):1229-42.

Agencia Europea del Medicamento (EMA). ERVEBBO. Ficha técnica o resumen de las características del producto [Internet]. Disponible en:

-World health Organization. R&D Blueprint [Internet]. Disponible en:

– The Coalition for Epidemic Preparedness Innovations (CEPI). [Internet]. Disponible en:

Wang Q, Zhang L, Kuwahara K, Li L, Liu Z, Li T, etal. Immunodominant SARS Coronavirus Epitopes in Humans Elicited both Enhancing and Neutralizing Effects on Infection in Non-human Primates. ACS Infect Dis. 13 de 2016;2(5):361-76.

Agrawal AS, Tao X, Algaissi A, Garron T, Narayanan K, Peng B-H, etal. Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus. Hum Vaccines Immunother. 2016;12(9):2351-6.

Tseng C-T, Sbrana E, Iwata-Yoshikawa N, Newman PC, Garron T, Atmar RL, etal. Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus. PloS One. 2012;7(4):e35421.

Bolles M, Deming D, Long K, Agnihothram S, Whitmore A, Ferris M, etal. A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge. J Virol. diciembre de 2011;85(23):12201-15.

-Polack FP. Atypical measles and enhanced respiratory syncytial virus disease (ERD) made simple. Pediatr Res. julio de 2007;62(1):111-5.

Tseng CTK, Huang C, Newman P, Wang N, Narayanan K, Watts DM, etal. Severe acute respiratory syndrome coronavirus infection of mice transgenic for the human Angiotensinconverting enzyme 2 virus receptor. J Virol. febrero de 2007;81(3):1162-73

Verity R, Okell LC, Dorigatti I, et al. Estimates of the severity of COVID-19 disease. medRxiv 2020;Available from

Can Lung US Help Critical Care Clinicians in the Early Diagnosis of Novel Coronavirus (COVID-19) Pneumonia?


Artículos periodísticos:

– Tomas Pueyo intenta refutar con este artículo al Imperial College:

“I’m Not An Epidemiologist But…”: The Rise Of The Coronavirus Influencers.  Pueyo is the first to tell you that he’s not a doctor nor a scientist. He’s the vice president of growth at Course Hero, an educational content sharing platform that allows students to collaborate on study notes — a process similar to the one he used to write “Coronavirus: Why You Must Act Now.”

–  “Se han adoptado contramedidas draconianas en muchos países. Si la pandemia se disipa, ya sea por sí sola o debido a estas medidas, el distanciamiento social extremo a corto plazo y los bloqueos pueden ser soportables. ¿Cuánto tiempo, sin embargo, deberían continuar las medidas como estas si la pandemia se agita en todo el mundo sin cesar? ¿Cómo pueden saber los políticos si están haciendo más bien que mal?”.  John P.A. Ioannidis

– A quién y cómo está afectando el COVID-19 en Italia y España:

– Italian scientists investigate possible earlier emergence of coronavirus:

Artículos científicos sobre las medidas:

– The effect of human mobility and control measures on the COVID-19 epidemic in China

The effect of human mobility and control measures on the COVID-19 epidemic in China.(Science)

– Distancia Social. The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study (The Lancet).

Report 11: Evidence of initialsuccessforChinaexiting COVID-19 social distancingpolicyafter achieving containment

Otros coronavirus :

Vincent C. C. Cheng, Susanna K. P. Lau, Patrick C. Y. Woo, Kwok Yung Yuen
– Hu, B., Ge, X., Wang, L. et al. Bat origin of human coronaviruses. Virol J 12, 221 (2015).
Utilidad de las cuarentenas generalizadas: